I haven't seen more than .1-.2 grains deviation on my auto disc with any powder I have used. I do stay away from stick powder as it does not meter well in it. I get a little leakage with H110 as it is a really fine ball, but still no real variation when checked with my RCBS beam scale.
I do use it in a turret press so it rides around the press from one bullet to another.
I dont think i would have any issues on a turret press where the measure would be seeing alot of movement. The auto drum has been working extremely well for me so far.