SheepDog4Life
Natural Gray Man
Hopefully the tide is turning.
I feel like we should pretend that Trump never said anything about any treatment and the treatments should be evaluated on their own merits (they are neither good, nor bad because Trump praised them)...but that's crazy talk these days.
As far as I can tell, there is a single study that showed the HCQ was not helpful and may have been harmful to patients who were extremely sick when the medication was started.
Meanwhile, there is mounting evidence (with studies which have been or are being peer reviewed) that when given with Zinc, HCQ can improve outcomes in those who have been exposed or whose COVID-19 has not yet become severe (an prophylactic antibiotic may be helpful in cases where a pneumonia is developing to keep lung fluid from becoming a breeding ground for bacteria, complicating the disease, but does not directly work "with" the HCQ).
As with all medical treatments, it will work in some situations better than others and may even harm in some...but that's why we do multiple studies under different conditions with different kinds of patients and different doses.
The main takeaway from the article is that most people don't understand what they're reading when they see these kinds of studies, and that lack of understanding is being manipulated (intentionally and unintentionally) for political purposes.
I'll stand on what I've asserted since the beginning, though: HCQ is a safe and effective treatment for COVID-19, when administered at the appropriate stage of infection - and primarily speaking, the people who claim that it is unsafe and/or ineffective simply don't know what they're talking about (or they do know, and are maliciously putting people's lives at risk because Orange Man Bad).
Concur with both of you.
The studies I've seen that show it causing harm, mostly heart arrhythmia, all involve extremely high dosing of 4-5x the maximum recommended safe dosing of 600 mg the first day (15x the normal dose). They have 2400-3000 mg cumulative doses in the first 24 hours...
THE DOSE MAKES THE POISON.
At 15x the recommended dose (15x2 pills = 30 full-size pills), ASPIRIN can be fatal for average/small adults!
And, most of those "negative" studies are hospitalized patients... who by definition have progressed past the "treat the virus" stage and require "treating the autoimmune response" treatments... two different treatments.
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