As much as ergonomics were a major reason for my prefering the P320 over the Glock I was predisposed to buy, I would contradict myself a bit and say that feel isn't even the most important thing-- especially for a SD gun.
If you can hit with it and it always works, it should be a candidate, even if you hate how it feels.
I've always found Glocks to be comfortable enough--not the best, but not needing to be, either.
Glock's are like Fat chicks, every body has had one