I have a g27 that I carry. really comfortable and I still feel like I'm carrying a good self defense round. I also keep a g23 under our bed. I like it for my wife because all she has to do is point and shoot. No safety to screw with and it fits in her hand good
My favorite is the G22 and I will tell you why. I shoot .40, .357 sig and 9mm through it. And its been absolutely reliable with factory ammo in all 3 calibers. I know sometimes you have to change ejectors to be able to shoot .40 and 9mm but not with the G22 I have. Grant you I only carry it stock but if I had to I would have confidence to defend myself with the 9mm conversion barrel and G17 mags in it shooting 9mm.
Got to love Glock