Full size, I feel that target re acquisition is much faster if I have a heavier gun with less muzzle jump and steadier in my hands especially with larger loads.
Full size and Compact are the ones that I shoot the most often. I would lean towards the compact as it fits my hands the best. It's the size that I carry and use for my nightstand gun so I have to be proficient with it.
Full size heavier 9mm, like my Beretta 92 or Sig 226. Just like being able to fire strings and keep them in or near the center ring. And I'd rather pay for 9mm than .45.
My Chiappa 1911 22lr pistol. Accurate, shoots Federal High Velocity all day
long with no issues, and it's cheap. Next would be my Bersa 380, because it
is so relliable and accurate, but expensive to shoot.
.44 in black powder but if i have to pick a smokeless then I would say it's close tie between the P226 or M&P or XD or .357 revolver or.... ah heck, i like em' all !