Traumagel

[Alamo]

FDA Grants 510(k) Clearance to Cresilon’s Traumagel for Temporary External Control of Moderate to Severe Bleeding

Cresilon works to stop life-threatening bleeding in seconds, offering a valuable tool for military, emergency medical services, and healthcare professionals.

www.pharmexec.com

First implemented as Vetigel:

VETIGEL - Cresilon

VETIGEL® is the first hemostatic gel for the veterinary market that stops bleeding in seconds. US veterinarians can order VETIGEL.

cresilon.com

Vetigel - Wikipedia

en.m.wikipedia.org

 

[foszoe]

FDA Grants 510(k) Clearance to Cresilon’s Traumagel for Temporary External Control of Moderate to Severe Bleeding

Cresilon works to stop life-threatening bleeding in seconds, offering a valuable tool for military, emergency medical services, and healthcare professionals.

www.pharmexec.com

First implemented as Vetigel:

VETIGEL - Cresilon

VETIGEL® is the first hemostatic gel for the veterinary market that stops bleeding in seconds. US veterinarians can order VETIGEL.

cresilon.com

Vetigel - Wikipedia

en.m.wikipedia.org

That is impressive. I wonder what the shelf life is?

 

[INP8riot]

I have had something similar to that in my med kit for years. It is quick clot in a syringe to put into a puncture type wound. That looks similar based on what I can tell just in gel form. That and a fox seal should greatly help any chest cavity non-planned entries.

Celox-A - Celox Medical

Injuries such as blast or knife wounds are very difficult to treat and often lethal. Celox™-A is a unique applicator delivery system pre-packed with 6g of Celox™ granules and designed to get directly to the bleeding site in just a few seconds. High-speed applicator for gunshot, blast or stab...

www.celoxmedical.com

 

[Alamo]

That is impressive. I wonder what the shelf life is?

Oneof the articles says 18 months.

 

[Alamo]

I have had something similar to that in my med kit for years. It is quick clot in a syringe to put into a puncture type wound. That looks similar based on what I can tell just in gel form. That and a fox seal should greatly help any chest cavity non-planned entries.

Celox-A - Celox Medical

Injuries such as blast or knife wounds are very difficult to treat and often lethal. Celox™-A is a unique applicator delivery system pre-packed with 6g of Celox™ granules and designed to get directly to the bleeding site in just a few seconds. High-speed applicator for gunshot, blast or stab...

www.celoxmedical.com

Celox works by adhering to tissue and physically blocking the bleed. Quickclot absorbs the water in blood and thereby concentrates the clotting factors in blood so they can form a clot. Both require holding direct pressure until they set up. The gauze versions require wound packing and the granules have to be dumped in and reach the bleeding site.

I can’t find what the mechanism for Traumagel is, whether it physically blocks the wound or works with clotting factors or something else.

Traumagel is a gel that is supposed to flow into the wound (via pressure from syringe), act in seconds, and not require pressure. So easier to apply and faster to work.

Also it is being tested by the Army as a first aid treatment for penetrating brain injuries. Right now not much you can do besides bandage the hole and get the patient to a neurosurgeon.

Hopefully it works out. I think it’s a good sign that the veterinary world has been using it for sometime now.

 

[2tonic]

Not to be impertinent, but I thought this treatment method was already addressed by putting the tampon machines in the boys bathrooms at inner city schools?

 

[Amishman44]

Celox works by adhering to tissue and physically blocking the bleed. Quickclot absorbs the water in blood and thereby concentrates the clotting factors in blood so they can form a clot. Both require holding direct pressure until they set up. The gauze versions require wound packing and the granules have to be dumped in and reach the bleeding site.

I can’t find what the mechanism for Traumagel is, whether it physically blocks the wound or works with clotting factors or something else.

Traumagel is a gel that is supposed to flow into the wound (via pressure from syringe), act in seconds, and not require pressure. So easier to apply and faster to work.

Also it is being tested by the Army as a first aid treatment for penetrating brain injuries. Right now not much you can do besides bandage the hole and get the patient to a neurosurgeon.

Hopefully it works out. I think it’s a good sign that the veterinary world has been using it for sometime now.

My question would be how deeply the gel will penetrate in relation to the depth of the wound so that, while it might stop external blood loss by preventing it from flowing freely out of the body, will it penetrate to the depth necessary to stop the bleed at its deepest point, so one doesn't continue bleed internally? I'd like to see some research on that with demonstrated results.
Head injuries...one has to be careful how much pressure ends up inside the cranium due to orbital blowout or pressure on the Pons and the Medulla Oblongata (ANS) of the brain stem.
Veterinary work would provide 'real-life' experience...I remember a USAF flight doc, back in the late '80's, who was training army field medics in SW Texas, they would take goats and sheep out and shoot them and the medics would have to work to keep them alive! Good real-life training.

 

[Alamo]

My question would be how deeply the gel will penetrate in relation to the depth of the wound so that, while it might stop external blood loss by preventing it from flowing freely out of the body, will it penetrate to the depth necessary to stop the bleed at its deepest point, so one doesn't continue bleed internally? I'd like to see some research on that with demonstrated results.

from what I’ve read, the point of making it a gel is so that it does flow to the deepest part of the wound, and this is why it’s in a syringe to provide the pressure to make the gel flow.

 

[Amishman44]

from what I’ve read, the point of making it a gel is so that it does flow to the deepest part of the wound, and this is why it’s in a syringe to provide the pressure to make the gel flow.

I understand...and it makes sense, but I would still like to read the research on that...especially in soft tissue, specifically the thoracic area where there's nothing solid to keep the gel flowing in a specific direction rather than simple press outward evenly in all directions - example, lung tissue filled with alveoli, capillary blood vessels, and other soft / squishy tissue, especially with a broken rib or two, reducing resistive compression, if that makes any sense? As a former volunteer EMT with 26 years' experience, in dealing with flail chest wounds, there's nothing to support lung function on the injured side, unless one creates the resistive barrier (aka, secure the rib motion via a compression wrap.)

 

[Somemedic]

I understand...and it makes sense, but I would still like to read the research on that...especially in soft tissue, specifically the thoracic area where there's nothing solid to keep the gel flowing in a specific direction rather than simple press outward evenly in all directions - example, lung tissue filled with alveoli, capillary blood vessels, and other soft / squishy tissue, especially with a broken rib or two, reducing resistive compression, if that makes any sense? As a former volunteer EMT with 26 years' experience, in dealing with flail chest wounds, there's nothing to support lung function on the injured side, unless one creates the resistive barrier (aka, secure the rib motion via a compression wrap.)

I'm guessing you wouldn't want a the gel in the lung tissue and becoming a thrombosis... riding up and occluding something.

We packed the footballs with the QClot gauze which made me realize if youre patient is conscious he's not gonna like you very much whilst you're doing this. That syringe applicator looks like it would be much less invasive and fairly quick. Won't be painless but snow em up with versed before you push the gel

 

[Somemedic]

I understand...and it makes sense, but I would still like to read the research on that...especially in soft tissue, specifically the thoracic area where there's nothing solid to keep the gel flowing in a specific direction rather than simple press outward evenly in all directions - example, lung tissue filled with alveoli, capillary blood vessels, and other soft / squishy tissue, especially with a broken rib or two, reducing resistive compression, if that makes any sense? As a former volunteer EMT with 26 years' experience, in dealing with flail chest wounds, there's nothing to support lung function on the injured side, unless one creates the resistive barrier (aka, secure the rib motion via a compression wrap.)

I'm guessing you wouldn't want a the gel in the lung tissue and becoming a thrombosis... riding up and occluding something.

We packed the footballs with the QClot gauze which made me realize if youre patient is conscious he's not gonna like you very much whilst you're doing this. That syringe applicator looks like it would be much less invasive and fairly quick. Won't be painless but snow em up with versed before you push the syringe

 

[Amishman44]

I'm guessing you wouldn't want a the gel in the lung tissue and becoming a thrombosis... riding up and occluding something.

We packed the footballs with the QClot gauze which made me realize if youre patient is conscious he's not gonna like you very much whilst you're doing this. That syringe applicator looks like it would be much less invasive and fairly quick. Won't be painless but snow em up with versed before you push the gel

Exactly...I just see secondary complications from this form of treatment, especially the potential of the gel becoming a thrombosis blocking other function.
Another question might be how well would it work in the event of a upper femoral artery laceration and retraction (example, GSW), where the actual blood loss will be in the lower abdominal cavity while the visible wound in the upper thigh?

 

[gassprint1]

Exactly...I just see secondary complications from this form of treatment, especially the potential of the gel becoming a thrombosis blocking other function.
Another question might be how well would it work in the event of a upper femoral artery laceration and retraction (example, GSW), where the actual blood loss will be in the lower abdominal cavity while the visible wound in the upper thigh?

I think another big concern would be, the surgeon missing some of the jel contained within blood vessels or arteries and sooner or later it creates a blockage in the heart of even the brain.

 

[Amishman44]

I think another big concern would be, the surgeon missing some of the jel contained within blood vessels or arteries and sooner or later it creates a blockage in the heart of even the brain.

Even the greatest of ideas (concepts) can have major residual consequences...I agree!

 

[Somemedic]

However....

If I'm bleeding the f out imma take some gel. We'll work the rest out later. I mean get me to a Level 1 and push the thrombolitics with some whole blood and a Tsurgeon in the room but I'll roll those dice