Buy a Taurus Judge. Who wants to fool with a long gun in the middle of the night. If you need a shotgun get a Serbu. If not try the Judge it shoots 410's or 45 long colts. In a house these are Ideal!
See what the penetration is from a .410 out of a 3" barrel before you espouse it's use. Try shooting a heavy winter coat or a leather jacket with a gallon water jug behind it from 10 feet.
You might be surprised at how weak it actually is.
.410's are notoriously worthless on game a lot of the time. Let alone trying to take down a 200 lb human. Nobody hunts deer with a .410 because it sucks at it.
.45LC is a good HD round but if the .410 is so ineffective, why bother with the judge?